Scientist, Embryology
Colossal Biosciences
The Embryology Scientist will spearhead groundbreaking research on techniques of embryo manipulation in non-model organisms.
This role works with talented reproductive biologists to continue to develop, implement, and maintain strategic plans of the embryology department. This position reports to the Director of Assisted Reproduction.
**This position is based out of Dallas, TX and relocation assistance is available within the US*
Duties and Responsibilities:
- Develop protocols for the in vitro production of embryos in mice, livestock, and a variety of novel, wildlife species.
- Production of embryos with edited genomes using a advanced ART including zygote microinjection, production of chimeras with ESC injection, and SCNT
- Derivation of embryonic stem cells, including development and optimization of protocols, from IVF, SCNT, and interspecies SCNT embryos.
- Collaborate with species and cell engineering teams to develop strategies for efficient production of embryos and offspring with desired gene alterations.
- Stay up to date on relevant literature, identify novel protocols/procedures that may be applicable for Colossal projects, and conduct associated experiments to continuously improve results.
- Maintain stable embryo development rates and troubleshoot protocols as needed.
- Some traveling required for training and implementing novel assisted reproductive technologies into non-model organisms
Required Skills and Abilities:
- Strong expertise in gamete, embryo, and/or stem cell biology.
- In vitro oocyte maturation, fertilization, embryo culture, nuclear transfer, and cryopreservation. Experience with multiple species, including non-traditional (wildlife) models preferred.
- Derivation and maintenance of embryonic stem cells, including extended culture, blastocyst microsurgery, and morphological, immunostaining, and molecular evaluation of viability and pluripotency.
- Strong communication skills (written/verbal)
- Ability to work independently, with members of the Embryology team, and members of other teams, as needed.
- At least three years of experience in the generation of genetically engineered model organisms (e.g., nuclear transfer, pronuclear and cytoplasmic injections of one-cell zygotes, electroporation of embryos, and/or ES cell injections blastocysts)
Education and Experience:
- Ph.D. or D.V.M. in biological sciences, veterinary medicine, bioengineering, molecular biology, genetics, or related field.
- Two years of post-doctoral experience.
- Demonstrated track-record of publication in peer-reviewed journals.
What Colossal Offers Full-Time Employees:
- Medical, dental, and vision coverage
- Excellent paid time off and company holidays so you can rest and recharge
- Flexible spending accounts (FSA)
- Company matched 401k retirement plan
- Paid parental leave at 100% salary for up to 12 weeks
- Education reimbursement
- An opportunity to help us return the Earth to a healthier state
The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.
Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.
Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.
Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.
Colossal is proud to be named a Best Place to Work by BuiltIn for 4 years in a row across multiple categories in 2023, 2024, 2025, and 2026:
- #1 on the 50 Best Startups to Work For in Dallas in 2023!
- 100 Best Midsize Places to Work in Dallas in 2024 & 2025
- 100 Best Places to Work in Dallas, TX (All Size Employers) in 2024, 2025, and 2026.
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Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!